An internal standard for the quantification of cefadroxil
Related Products
Unlabeled Version(s)
20365Cefadroxil (hydrate)
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Cefadroxil-d4 (trifluoroacetate salt)

Item No. 33380

Technical Information
Formal Name
(6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl-2,3,5,6-d4)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular Formula
C16H13D4N3O5S • CF3COOH
Formula Weight
Purity
≥99% deuterated forms (d1-d4)
A solid
DMSO: solubleMethanol: solubleWater: soluble
SMILES
OC1=C([2H])C([2H])=C([C@@H](N)C(N[C@@H]2C(N3[C@]2([H])SCC(C)=C3C(O)=O)=O)=O)C([2H])=C1[2H].OC(C(F)(F)F)=O
InChi Code
InChI=1S/C16H17N3O5S.C2HF3O2/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;3-2(4,5)1(6)7/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);(H,6,7)/t10-,11-,15-;/m1./s1/i2D,3D,4D,5D;
InChi Key
PQRAWSCYCASBIK-AUTKPGNWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cefadroxil-d4 is intended for use as an internal standard for the quantification of cefadroxil (Item No. 20365) by GC- or LC-MS. Cefadroxil is a semisynthetic cephalosporin antibiotic.1 It is active against a variety of Gram-positive and Gram-negative bacteria, including B. anthracis, V. cholerae, and P. multocida strains (MICs = 1, 2, and 4 µg/ml, respectively), among others. Cefadroxil is protective against infection by strains of S. pyogenes, S. pneumoniae, or S. aureus in mice with 50% protective dose (PD50) values of 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively. Formulations containing cefadroxil have been used in the treatment of a variety of bacterial infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Buck, R.E., and Price, K.E. Cefadroxil, a new broad-spectrum cephalosporin. Antimicrob. Agents Chemother. 11(2), 324-330 (1977).