A bile acid
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7,12-Diketolithocholic Acid

Item No. 33416

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5β)-3α-hydroxy-7,12-dioxo-cholan-24-oic acid
CAS Number
517-33-9
Synonyms
  • 7,12-Dioxolithocholic Acid
  • 3-hydroxy-7,12-Diketocholanoic Acid
  • 7,12-diketo-LCA
Molecular Formula
C24H36O5
Formula Weight
404.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: slightly solubleWater: slightly soluble
SMILES
O=C1[C@@]2([H])[C@@]3([H])[C@@]([C@]([C@@H](CCC(O)=O)C)([H])CC3)(C(C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)=O)C
InChi Code
InChI=1S/C24H36O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-18,22,25H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,22+,23+,24-/m1/s1
InChi Key
MAFJMPFLJJCSTB-FQBQTYDJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    Product Description

    7,12-Diketolithocholic acid is a bile acid.1 Plasma levels of 7,12-diketolithocholic acid are increased in patients with cholestasis.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, T., Wang, R.-X., Han, J., et al. Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations. Liver Int. 38(9), 1676-1685 (2018).