An antibacterial hydroxy fatty acid
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7(S),10(S)-DiHOME

Item No. 33447

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7S,10S-dihydroxy-8E-octadecenoic acid
CAS Number
252255-87-1
Synonyms
  • DHOE
  • DOD
Molecular Formula
C18H34O4
Formula Weight
314.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 15 mg/mlDMSO: 20 mg/mlEthanol: 100 mg/mlPBS (pH 7.2): 0.25 mg/ml
SMILES
CCCCCCCC[C@H](O)/C=C/[C@@H](O)CCCCCC(O)=O
InChi Code
InChI=1S/C18H34O4/c1-2-3-4-5-6-8-11-16(19)14-15-17(20)12-9-7-10-13-18(21)22/h14-17,19-20H,2-13H2,1H3,(H,21,22)/b15-14+/t16-,17-/m0/s1
InChi Key
IPRLELFMTNDNMN-WLFRDLTRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $38

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    5 mg

    $165

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    10 mg

    $291

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    Product Description

    7(S),10(S)-DiHOME is a hydroxy fatty acid and metabolite of oleic acid (Item Nos. 90260 | 24659) that is produced by P. aeruginosa from vegetable oils.1 It is active against the food-borne pathogenic bacteria S. aureus, S. typhimurium, L. monocytogenes, B. subtilis, and E. coli (MIC50s = 31.3, 125, 125, 62.5, and 250 µg/ml, respectively), as well as the plant pathogenic bacteria Erwinia, R. solanacearum, C. glutamicum, and P. syringae (MIC90s = 125, 125, 250, and 500 µg/ml, respectively).2,1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sohn, H.-R., Bae, J.-H., Hou, C.T., et al. Antibacterial activity of a 7,10-dihydroxy-8(E)-octadecenoic acid against plant pathogenic bacteria. Enzyme Microb. Technol. 53(3), 152-153 (2013).

    2. Chen, K.Y., Kim, I.H., Hou, C.T., et al. Monoacylglycerol of 7,10-dihydroxy-8(E)-octadecenoic acid enhances antibacterial activities against food-borne bacteria. J. Agric. Food Chem. 67(29), 8191-8196 (2019).