A fungal metabolite
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

WF-3681

Item No. 33523

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,5-dihydro-4-hydroxy-5-oxo-3-phenyl-2-furanpropanoic acid
CAS Number
105364-56-5
Synonyms
  • (±)-WF-3681
Molecular Formula
C13H12O5
Formula Weight
248.2
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
O=C1C(O)=C(C2=CC=CC=C2)C(CCC(O)=O)O1
InChi Code
InChI=1S/C13H12O5/c14-10(15)7-6-9-11(12(16)13(17)18-9)8-4-2-1-3-5-8/h1-5,9,16H,6-7H2,(H,14,15)
InChi Key
PPZVSYXNLXFYAD-UHFFFAOYSA-N
Origin
Fungus/Chaetomella sp
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µg

    $202

    Add

    500 µg

    $648

    Add
    Product Description

    WF-3681 is a butenolide fungal metabolite that has been found in Acremonium.1 It inhibits aldose reductase (IC50 = 0.25 µM for the rabbit lens enzyme).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ghisalberti, E.L., Hargreaves, J.R., and McConville, E. Butenolides from a cultured microfungus, Acremonium sp. Nat. Prod. Res. 18(2), 105-109 (2004).

    2. Nishikawa, M., Yoshida, K., Okamoto, M., et al. Studies on WE-3681, a novel aldose reductase inhibitor. III. Effects of WF-3681 and its derivatives on sorbitol accumulation in diabetic rats. J. Antibiot. (Tokyo) 43(9), 1186-1188 (1990).