An MRI contrast agent
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Gadoteridol

Item No. 33577

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
[10-[2-(hydroxy-κO)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-κN1,κN4,κN7,κN10,κO1,κO4,κO7]-gadolinium
CAS Number
120066-54-8
Synonyms
  • Gd-HP-D03A
  • SQ 32,692
Molecular Formula
C17H29GdN4O7
Formula Weight
558.7
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
CC1[OH][Gd+3]([N](CC2)(CC3)CC4=O)([N]53CC6=O)([N]72C1)([O-]6)([O-]4)([O-]8)[N](CC7)(CC5)CC8=O
InChi Code
InChI=1S/C17H32N4O7.Gd/c1-14(22)10-18-2-4-19(11-15(23)24)6-8-21(13-17(27)28)9-7-20(5-3-18)12-16(25)26;/h14,22H,2-13H2,1H3,(H,23,24)(H,25,26)(H,27,28);/q;+3/p-3
InChi Key
DPNNNPAKRZOSMO-UHFFFAOYSA-K
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $81

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    100 mg

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    500 mg

    $475

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    Cayman Chemical
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    Product Description

    Gadoteridol is a gadolinium-based MRI contrast agent.1,2 It enhances the visibility of intraparenchymal and meningeal tumors in an orthotopic rat model of brain cancer when administered at a dose of 0.25 mmol/kg.1 In vitro labeling of murine mesenchymal stem cells (MSCs) with gadoteridol and subsequent injection into mice has been used to track their migration to spinal cord injury lesions in vivo.2 Formulations containing gadoteridol have been used to visualize intra- and extracranial lesions in the head, neck, and spine.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Runge, V.M., Gelblum, D.Y., and Jacobson, S. Gd HP-DO3A—experimental evaluation in brain and renal MR. Magn. Reson. Imaging 9(1), 79-87 (1991).

    2. Filippi, M., Boido, M., Pasquino, C., et al. Successful in vivo MRI tracking of MSCs labeled with gadoteridol in a spinal cord Injury experimental model. Exp. Neurol. 282, 66-77 (2016).