A medium-chain saturated fatty acid
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Octanoic Acid

Item No. 33674

Technical Information
CAS Number
124-07-2
Synonyms
  • Caprylic Acid
  • C8:0
  • FA 8:0
Molecular Formula
C8H16O2
Formula Weight
Purity
≥99%
A liquid
Methanol: soluble
SMILES
O=C(CCCCCCC)O
InChi Code
InChI=1S/C8H16O2/c1-2-3-4-5-6-7-8(9)10/h2-7H2,1H3,(H,9,10)
InChi Key
WWZKQHOCKIZLMA-UHFFFAOYSA-N
Side Chain Carbon Sum
8:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.3,4 [Matreya, LLC. Catalog No. 1198]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mallatou, H., Pappa, E., and Massouras, T. Changes in free fatty acids during ripening of Teleme cheese made with ewes’, goats’, cows’ or a mixture of ewes’ and goats’ milk. Int. Dairy J. 13(1-3), 211-219 (2003).

    2. Hyang, C.B., Alimova, Y., Myers, T.M., et alShort- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. Arch. Oral Biol. 56(7), 650-654 (2011).

    3. Onkenhout, W., Venizelos, V., van der Poel, P.F.H., et alIdentification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. Clin. Chem. 41(10), 1467-1474 (1995).

    4. Rinaldo, P., O'Shea, J.J., Coates, P.M., et alMedium-chain acyl-CoA dehydrogenase deficiency. Diagnosis by stable-isotope dilution measurement of urinary n-hexanoylglycine and 3-phenylpropionylglycine. N. Engl. J. Med. 319(20), 1308-1313 (1988).