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Serotonin (hydrochloride)

Item No. 33680

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 5-HT
  • 5-Hydroxytryptamine
Technical Information
Formal Name
3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride
CAS Number
153-98-0
Molecular Formula
C10H12N2O • HCl
Formula Weight
212.7
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 11 mg/mlDMSO: 11 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
221 nm
SMILES
OC1=CC2=C(NC=C2CCN)C=C1.Cl
InChi Code
InChI=1S/C10H12N2O.ClH/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;/h1-2,5-6,12-13H,3-4,11H2;1H
InChi Key
MDIGAZPGKJFIAH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $49

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    Product Description

    Serotonin (hydrochloride) is an analytical reference standard categorized as a tryptamine. Serotonin levels are increased in opioid-associated serotonin syndrome.1 This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 14332).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baldo, B.A. Opioid analgesic drugs and serotonin toxicity (syndrome): Mechanisms, animal models, and links to clinical effects. Arch. Toxicol. 92(8), 2457-2473 (2018).

    Product Citations

    Kozell, L.B., Eshleman, A.J., Swanson, T.L., et al. Pharmacologic activity of substituted tryptamines at 5-HT2AR, 5-HT2CR, 5-HT1AR, and SERT. J. Pharmacol. Exp. Ther. JPET-AR-2022-001454 (2023).