A potential impurity found in commercial preparations of olanzapine
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Olanzapine-related Compound B

Item No. 33786

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5,10-dihydro-2-methyl-4H-thieno[2,3-b][1,5]benzodiazepin-4-one
CAS Number
221176-49-4
Synonyms
  • LY301664
Molecular Formula
C12H10N2OS
Formula Weight
230.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:3): 0.25 mg/mlEthanol: 15 mg/ml
λmax
231, 262 nm
SMILES
O=C1NC2=C(NC3=C1C=C(C)S3)C=CC=C2
InChi Code
InChI=1S/C12H10N2OS/c1-7-6-8-11(15)13-9-4-2-3-5-10(9)14-12(8)16-7/h2-6,14H,1H3,(H,13,15)
InChi Key
LVTDAJJOMLNXFS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $219

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    10 mg

    $394

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    25 mg

    $821

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    50 mg

    $1,095

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    Product Description

    Olanzapine-related compound B is a potential impurity found in commercial preparations of olanzapine.1 It is a degradation product formed by exposure to oxidative stress.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hiriyanna, S.G., Basavaiah, K., Goud, P.S.K., et al. Identification and characterization of olanzapine degradation products under oxidative stress conditions. Acta Chromatagr. 20(1), 81–93 (2008).