An alkaloid with anti-inflammatory activity
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Isomer(s)
31169Anagyrine
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Thermopsine

Item No. 33853

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(7R,14R,14aS)-1,3,4,6,7,13,14,14a-octahydro-7,14-methano-2H,11H-dipyrido[1,2-a:1′,2′-e][1,5]diazocin-11-one
CAS Number
486-90-8
Synonyms
  • NSC 21725
  • (-)-Thermopsine
Molecular Formula
C15H20N2O
Formula Weight
244.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
234, 311 nm
SMILES
O=C1N(C2=CC=C1)C[C@]3([H])[C@]4([H])CCCCN4C[C@@]2([H])C3
InChi Code
InChI=1S/C15H20N2O/c18-15-6-3-5-14-11-8-12(10-17(14)15)13-4-1-2-7-16(13)9-11/h3,5-6,11-13H,1-2,4,7-10H2/t11-,12-,13+/m1/s1
InChi Key
FQEQMASDZFXSJI-UPJWGTAASA-N
Origin
Plant/Paeonia lactiflora Pall. root
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Thermopsine is an alkaloid that has been found in Sophora tonkinensis and has anti-inflammatory activity.1 It reduces LPS-induced production of TNF-α in RAW 264.7 cells when used at a concentration of 50 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. He, L.-J., Liu, J.-S., Luo, D., et al. Quinolizidine alkaloids from Sophora tonkinensis and their anti-inflammatory activities. Fitoterapia 139, 104391 (2019).