A monolignol with anti-inflammatory and antinociceptive activities
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Sinapyl Alcohol

Item No. 33916

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-(3-hydroxy-1-propen-1-yl)-2,6-dimethoxy-phenol
CAS Number
537-33-7
Molecular Formula
C11H14O4
Formula Weight
210.2
Purity
≥95%
Formulation (Request formulation change)
A solid (stabilized with MEHQ, 0.2% w/w)
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
223, 276 nm
SMILES
OC1=C(OC)C=C(C=CCO)C=C1OC
InChi Code
InChI=1S/C11H14O4/c1-14-9-6-8(4-3-5-12)7-10(15-2)11(9)13/h3-4,6-7,12-13H,5H2,1-2H3
InChi Key
LZFOPEXOUVTGJS-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 mg

    $63

    Add

    50 mg

    $110

    Add

    100 mg

    $195

    Add

    250 mg

    $423

    Add
    Product Description

    Sinapyl alcohol is a monolignol and an aglycone form of syringin (Item No. 22387) that has been found in Populus alba and has anti-inflammatory and antinociceptive activities.1,2 It is a precursor in the biosynthesis of lignin.1 Sinapyl alcohol (50, 100, and 200 µM) reduces LPS-induced production of nitrite, prostaglandin E2 (PGE2; Item No. 14010), and TNF-α in RAW 264.7 cells.2 Sinapyl alcohol (20 and 30 mg/kg) inhibits acetic acid-induced writhing and increases the latency to paw licking in the hot plate test in mice.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shigeto, J., Ueda, Y., Sasaki, S., et al. Enzymatic activities for lignin monomer intermediates highlight the biosynthetic pathway of syringyl monomers in Robinia pseudoacacia. J. Plant Res. 130(1), 203-210 (2017).

    2. Choi, J., Shin, K.-M., Park, H.-J., et al. Anti-inflammatory and antinociceptive effects of sinapyl alcohol and its glucoside syringin. Planta Med. 70(11), 1027-1032 (2004).