A synthetic GHRH peptide
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Somatorelin (1-44) amide (human) (trifluoroacetate salt)

Item No. 33942

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
somatoliberin (human pancreatic islet), trifluoroacetate salt
Synonyms
  • Growth Hormone-releasing Factor (1-44) amide
  • hpGRF-44
  • Human Pancreas GRF-44
  • Somatoliberin
Molecular Formula
C215H358N72O66S • XCF3COOH
Formula Weight
5039.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 10 mg/ml
SMILES
O=C([C@@H](N)CC1=CC=C(C=C1)O)N[C@@H](C)C(N[C@H](C(N[C@@H](C)C(N[C@@]([H])([C@H](CC)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@]([H])(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@@]([H])([C@H](CC)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](C)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(N)=O)=O)CO)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CO)=O)CCSC)=O)=O)CC(O)=O)=O)CCC(N)=O)=O)=O)=O)CCCCN[H])=O)CCCNC(N)=N)=O)=O)CO)=O)=O)CCC(N)=O)=O)=O)=O)C(C)C)=O)CCCCN[H])=O)CCCNC(N)=N)=O)CC3=CC=C(C=C3)O)=O)CO)=O)CC(N)=O)=O)[C@@H](C)O)=O)=O)=O)=O)CC(O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C215H358N72O66S.C2HF3O2/c1-24-106(15)166(285-174(318)112(21)251-193(337)145(91-163(309)310)270-173(317)109(18)249-175(319)119(218)86-115-49-53-117(293)54-50-115)208(352)278-142(87-114-39-27-26-28-40-114)200(344)287-168(113(22)292)209(353)279-144(90-157(225)301)199(343)283-150(99-291)204(348)274-141(88-116-51-55-118(294)56-52-116)197(341)261-126(47-37-78-243-214(235)236)181(325)260-122(42-30-32-73-217)192(336)284-165(105(13)14)206(350)277-137(82-101(5)6)178(322)247-95-160(304)253-129(58-65-152(220)296)185(329)272-140(85-104(11)12)196(340)282-147(96-288)202(346)252-111(20)172(316)256-124(45-35-76-241-212(231)232)180(324)259-121(41-29-31-72-216)184(328)271-139(84-103(9)10)195(339)273-138(83-102(7)8)194(338)266-133(61-68-155(223)299)190(334)276-146(92-164(311)312)201(345)286-167(107(16)25-2)207(351)268-135(71-80-354-23)191(335)281-148(97-289)203(347)262-127(48-38-79-244-215(237)238)182(326)264-131(59-66-153(221)297)187(331)263-128(57-64-151(219)295)177(321)246-94-159(303)254-130(62-69-161(305)306)186(330)280-149(98-290)205(349)275-143(89-156(224)300)198(342)267-132(60-67-154(222)298)188(332)265-134(63-70-162(307)308)189(333)258-120(43-33-74-239-210(227)228)176(320)245-93-158(302)248-108(17)170(314)255-123(44-34-75-240-211(229)230)179(323)250-110(19)171(315)257-125(46-36-77-242-213(233)234)183(327)269-136(169(226)313)81-100(3)4;3-2(4,5)1(6)7/h26-28,39-40,49-56,100-113,119-150,165-168,288-294H,24-25,29-38,41-48,57-99,216-218H2,1-23H3,(H2,219,295)(H2,220,296)(H2,221,297)(H2,222,298)(H2,223,299)(H2,224,300)(H2,225,301)(H2,226,313)(H,245,320)(H,246,321)(H,247,322)(H,248,302)(H,249,319)(H,250,323)(H,251,337)(H,252,346)(H,253,304)(H,254,303)(H,255,314)(H,256,316)(H,257,315)(H,258,333)(H,259,324)(H,260,325)(H,261,341)(H,262,347)(H,263,331)(H,264,326)(H,265,332)(H,266,338)(H,267,342)(H,268,351)(H,269,327)(H,270,317)(H,271,328)(H,272,329)(H,273,339)(H,274,348)(H,275,349)(H,276,334)(H,277,350)(H,278,352)(H,279,353)(H,280,330)(H,281,335)(H,282,340)(H,283,343)(H,284,336)(H,
InChi Key
JHPMUHGRHBRHDB-GZQZBPRGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $267

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    1 mg

    $505

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    Product Description

    Somatorelin (1-44) amide is a synthetic peptide that corresponds to the full 44-amino acid sequence of growth hormone-releasing hormone (GHRH), a hormone that stimulates the production of growth hormone from the pituitary gland and is involved in the regulation of cell proliferation and differentiation.1,2 Somatorelin induces growth hormone release similarly to GHRH in vitro and in vivo.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Guillemin, R., Brazeau, P., Böhlen, P., et al. Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly. Science 218(4572), 585-587 (1982).

    2. Kiaris, H., Chatzistamou, I., Papavassiliou, A.G., et al. Growth hormone-releasing hormone: Not only a neurohormone. Trends Endocrinol. Metab. 22(8), 311-317 (2011).