An internal standard for the quantification of naphazoline
Related Products
Unlabeled Version(s)
23774Naphazoline (hydrochloride)
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Naphazoline-d4 (hydrochloride)

Item No. 34012

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4,5-dihydro-2-(1-naphthalenylmethyl)-1H-imidazole-4,4,5,5-d4, monohydrochloride
Synonyms
  • 2-(1-Naphthylmethyl)-2-imidazoline-d4
Molecular Formula
C14H10D4N2 • HCl
Formula Weight
250.8
Purity
≥99% deuterated forms (d1-d4)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: soluble
SMILES
[2H]C1([2H])NC(CC2=CC=CC3=C2C=CC=C3)=NC1([2H])[2H].Cl
InChi Code
InChI=1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H,8-10H2,(H,15,16);1H/i8D2,9D2;
InChi Key
DJDFFEBSKJCGHC-JRWKTVICSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $134

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    1 mg

    $253

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    5 mg

    $994

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    Product Description

    Naphazoline-d4 is intended for use as an internal standard for the quantification of naphazoline (Item No. 23774) by GC- or LC-MS. Naphazoline is a vasoconstrictor.1 In vivo, naphazoline (0.1 mg/kg, i.v.) decreases specific airway resistance and reverses intranasal blockage induced by U-46619 (Item No. 16450) or leukotriene D4 (LTD4; Item No. 20310) in guinea pigs. Formulations containing naphazoline have been used to treat allergic conjunctivitis and as nasal decongestants.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tanaka, Y., Mizutani, N., Fujii, M., et al. Different mechanisms between thromboxane A2- and leukotriene D4-induced nasal blockage in guinea pigs. Prostaglandins Other Lipid Mediat. 80(3-4), 144-154 (2006).