A polyphenolic flavonoid
Related Products
Isomer(s)
33964Isoflavone
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Flavone

Item No. 34028

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-phenyl-4H-1-benzopyran-4-one
CAS Number
525-82-6
Synonyms
  • NSC 19028
  • 2-Pheylchormone
Molecular Formula
C15H10O2
Formula Weight
222.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:6): 0.14 mg/ml
λmax
251, 296 nm
SMILES
O=C1C=C(C2=CC=CC=C2)OC3=C1C=CC=C3
InChi Code
InChI=1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H
InChi Key
VHBFFQKBGNRLFZ-UHFFFAOYSA-N
Origin
Plant/Unidentified sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 g

    $69

    Add

    10 g

    $127

    Add

    25 g

    $297

    Add

    50 g

    $525

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    Flavone is a polyketide synthase-derived polyphenolic flavonoid that has been found in various edible plants.1 It is the backbone scaffold of many pharmacologically active flavonoids, including luteolin (Item No. 10004161), apigenin (Item No. 10010275), and wogonin (Item No. 14248).1,2 Flavone reduces proliferation of (EC50 = 54.8 µM), and induces apoptosis in, HT-29 colon cancer cells.1 It enhances dengue virus type 2 (DENV-2) infectivity in Vero cells when used at a concentration of 100 µg/ml.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wenzel, U., Kuntz, S., Brendel, M.D., et al. Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells. Cancer Res. 60(14), 3823-3831 (2000).

    2. Zandi, K., Lani, R., Wong, P.-F., et al. Flavone enhances dengue virus type-2 (NGC strain) infectivity and replication in Vero cells. Molecules 17(3), 2437-2445 (2012).