A glycopeptide antibiotic
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N-Demethylvancomycin (hydrochloride)

Item No. 34119

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
56-demethyl-vancomycin, hydrochloride
CAS Number
198774-23-1
Synonyms
  • A51568A
  • Norvancomycin
Molecular Formula
C65H73Cl2N9O24 • XHCl
Formula Weight
1435.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: 10 mg/mlPBS (pH 7.2): 1 mg/ml
SMILES
ClC1=CC([C@H]([C@H](C(N[C@H](C(N[C@@]2([H])C(N[C@@](C3=CC=C(O)C4=C3)([H])C5=O)=O)=O)CC(N)=O)=O)NC([C@H](N)CC(C)C)=O)O)=CC=C1OC6=C(C(OC7=CC=C(C=C7Cl)[C@@H](O)[C@@]([H])(C(N[C@H](C(O)=O)C8=CC(O)=CC(O)=C84)=O)N5)=CC2=C6)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O[C@H]%10C[C@](N)([C@@H]([C@@H](O%10)C)O)C.Cl
InChi Code
InChI=1S/C65H73Cl2N9O24.ClH/c1-22(2)11-33(68)57(87)75-48-50(82)25-6-9-37(31(66)13-25)96-39-15-27-16-40(54(39)100-64-55(53(85)52(84)41(21-77)98-64)99-43-20-65(4,70)56(86)23(3)95-43)97-38-10-7-26(14-32(38)67)51(83)49-62(92)74-47(63(93)94)30-17-28(78)18-36(80)44(30)29-12-24(5-8-35(29)79)45(59(89)76-49)73-60(90)46(27)72-58(88)34(19-42(69)81)71-61(48)91;/h5-10,12-18,22-23,33-34,41,43,45-53,55-56,64,77-80,82-86H,11,19-21,68,70H2,1-4H3,(H2,69,81)(H,71,91)(H,72,88)(H,73,90)(H,74,92)(H,75,87)(H,76,89)(H,93,94);1H/t23-,33+,34-,41+,43-,45+,46+,47-,48+,49-,50+,51+,52+,53-,55+,56+,64-,65-;/m0./s1
InChi Key
LLWFHCJFZGXUAT-UMXPSMRGSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    N-Demethylvancomycin is a glycopeptide antibiotic that has been found in Nocardia orientalis.1 It is active against several strains of S. aureus and S. epidermidis in vitro and in vivo.2 Formulations containing N-demethylvancomycin have been used in the treatment of bacterial infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Boeck, L.D., Mertz, F.P., Wolter, R.K., et al. N-demethylvancomycin, a novel antibiotic produced by a strain of Nocardia orientalis. Taxonomy and fermentation. J. Antibiot. (Tokyo) 37(5), 446-453 (1984).

    2. Hunt, A.H., Marconi, G.G., Elzey, T.K., et al. A51568A: N-demethylvancomycin. J. Antibiot. (Tokyo) 37(8), 917-919 (1984).