A metabolite of dopamine
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Product Categories

Product Type

Biochemicals

Research Area

Cardiovascular System
Blood
Neuroscience

Dopamine 3-O-Sulfate

Item No. 34129

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-(2-aminoethyl)-1,2-benzenediol 2-(hydrogen sulfate)
CAS Number
51317-41-0
Synonyms
  • DA-3S
  • Dopamine 3-Sulfate
Molecular Formula
C8H11NO5S
Formula Weight
233.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: slightly solubleMethanol: slightly soluble
SMILES
O=S(O)(OC1=CC(CCN)=CC=C1O)=O
InChi Code
InChI=1S/C8H11NO5S/c9-4-3-6-1-2-7(10)8(5-6)14-15(11,12)13/h1-2,5,10H,3-4,9H2,(H,11,12,13)
InChi Key
NZKRYJGNYPYXJZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $54

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    1 mg

    $102

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    Product Description

    Dopamine 3-O-sulfate is a metabolite of the endogenous catecholamine dopamine (Item No. 21992).1 It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3.2 Dopamine 3-O-sulfate is found at higher levels in the brain and circulation than dopamine 4-O-sulfate.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Suominen, T., Uutela, P., Ketola, R.A., et al. Determination of serotonin and dopamine metabolites in human brain microdialysis and cerebrospinal fluid samples by UPLC-MS/MS: Discovery of intact glucuronide and sulfate conjugates. PLoS One 8(6), e68007 (2013).

    2. Itäaho, K., Alakurtti, S., Yli-Kauhaluoma, J., et al. Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation. Biochem. Pharmacol. 74(3), 504-510 (2007).