A synthetic precursor

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Product Categories

Product Type

Biochemicals

Synthetic Intermediates & Building Blocks

Research Area

Immunology & Inflammation

(R)-(+)-Trityl glycidyl ether

Name: (R)-(+)-Trityl glycidyl ether
Brand: -

Item No. 34131

(R)-(+)-Trityl glycidyl ether ((R)-Trityl Glycidol, CAS Number: 65291-30-7)

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)

Technical Information

Formal Name

2R-[(triphenylmethoxy)methyl]-oxirane

CAS Number

65291-30-7

Synonyms

(R)-Trityl Glycidol

Molecular Formula

C₂₂H₂₀O₂

Formula Weight

316.4

Purity

≥98%

Formulation (Request formulation change)

A solid

Solubility(Learn about Variance in Solubility)

DMF: 10 mg/mlDMSO: 1 mg/ml

SMILES

[C@@H]1(CO1)COC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4

InChi Code

InChI=1S/C22H20O2/c1-4-10-18(11-5-1)22(24-17-21-16-23-21,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,21H,16-17H2/t21-/m1/s1

InChi Key

XFSXUCMYFWZRAF-OAQYLSRUSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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1 g

$54

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5 g

$185

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Product Description

(R)-(+)-Trityl glycidyl ether is a precursor that has been used in the synthesis of glycerophospholipids, as well as compounds with antiviral and antimalarial activities.^1,2,3

WARNING This product is not for human or veterinary use.

References & Product Citations

Product Description References

1. Hendrickson, H.S., and Hendrickson, E.K. A facile asymmetric synthesis of glycerol phospholipids via tritylglycidol prepared by the asymmetric epoxidation of allyl alcohol. Thiolester and thioether analogs of phosphatidylcholine. Chem. Phys. Lipids 53(1), 115-120 (1990).

2. Baszczyňski, O., Jansa, P., Dračínský, M., et al. Synthesis and antiviral activity of N9-[3-fluoro-2-(phosphonomethoxy)propyl] analogues derived from N6-substituted adenines and 2,6-diaminopurines. Bioorg. Med. Chem. 19(7), 2114-2124 (2011).

3. Sato, E., Morita, M., Ogawa, H., et al. Design, synthesis and anti-malarial activities of synthetic analogs of biselyngbyolide B, a Ca²⁺ pump inhibitor from marine cyanobacteria. Bioorg. Med. Chem. Lett. 28(3), 298-301 (2018).

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