An active metabolite of ropinirole
Related Products
Parent Compound(s)
23871Ropinirole (hydrochloride)
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

N-Despropyl Ropinirole

Item No. 34156

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,3-dihydro-4-[2-(propylamino)ethyl]-2H-indol-2-one
CAS Number
106916-16-9
Synonyms
  • SKF 104557
Molecular Formula
C13H18N2O
Formula Weight
218.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:4): 0.2 mg/mlEthanol: 1 mg/ml
λmax
251 nm
SMILES
O=C1NC2=CC=CC(CCNCCC)=C2C1
InChi Code
InChI=1S/C13H18N2O/c1-2-7-14-8-6-10-4-3-5-12-11(10)9-13(16)15-12/h3-5,14H,2,6-9H2,1H3,(H,15,16)
InChi Key
VKDWFHAQOZYATG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $185

    Add

    10 mg

    $258

    Add

    25 mg

    $597

    Add

    50 mg

    $1,098

    Add
    Product Description

    N-Despropyl ropinirole is an active metabolite of the dopamine D2 receptor agonist ropinirole (Item No. 23871).1 It increases extracellular acidification rates in CHO cells expressing human dopamine D2, D3, and D4 receptors (EC50s = 0.63, 0.063, and 1.23 µM, respectively). N-Despropyl ropinirole is also a potential impurity found in commercial preparations of ropinirole.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Coldwell, M.C., Boyfield, I., Brown, T., et al. Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cells. Br. J. Pharmacol. 127(7), 1696-1702 (1999).

    2. Coufal, P., Stulik, K., Claessens, H.A., et al. Separation and quantification of ropinirole and some impurities using capillary liquid chromatography. J. Chromatogr. B Biomed. Sci. Appl. 732(2), 437-444 (1999).