An Analytical Reference Standard
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33839Nuciferine
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Nuciferine

Item No. 34221

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • (–)-Nuciferine
  • Sanjoinine E
  • VLT 049
Technical Information
Formal Name
5,6,6aR,7-tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
CAS Number
475-83-2
Molecular Formula
C19H21NO2
Formula Weight
295.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 1 mg/mlDMSO:PBS (pH 7.2) (1:3): 0.25 mg/mlEthanol: slightly soluble
λmax
272 nm
SMILES
COC1=C2C3=C(C=C1OC)CCN(C)[C@]3([H])CC4=CC=CC=C42
InChi Code
InChI=1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1
InChi Key
ORJVQPIHKOARKV-OAHLLOKOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Nuciferine (Item No. 34221) is an analytical reference standard categorized as an alkaloid.1 Nuciferine induces sedation, hypothermia, ptosis, and catalepsy in rodents. It has been found in refillable non-nicotinic vaping mixtures for electronic cigarettes.2 This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 33839).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bhattacharya, S.K., Bose, R., Ghosh, P., et al. Psychopharmacological studies on (–)-nuciferine and its Hofmann degradation product atherosperminine. Psychopharmacology (Berl.) 59(1), 29-33 (1978).

    2. Holt, A.K., Poklis, J.L., and Peace, M.R. A retrospective analysis of chemical constituents in regulated and unregulated e-cigarette liquids. Front. Chem. 9, 752342 (2021).