A broad-spectrum cephalosporin antibiotic
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Cefquinome (sulfate)

Item No. 34266

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-5,6,7,8-tetrahydro-quinolinium, monosulfate
CAS Number
118443-89-3
Synonyms
  • HR 111V sulfate
Molecular Formula
C23H25N6O5S2 • HSO4
Formula Weight
626.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml
λmax
267 nm
SMILES
O=C(/C(C1=CSC(N)=N1)=N\OC)N[C@H](C2=O)[C@]3([H])N2C(C(O)=O)=C(C[N+]4=C(CCCC5)C5=CC=C4)CS3.O=S([O-])(O)=O
InChi Code
InChI=1S/C23H24N6O5S2.H2O4S/c1-34-27-16(14-11-36-23(24)25-14)19(30)26-17-20(31)29-18(22(32)33)13(10-35-21(17)29)9-28-8-4-6-12-5-2-3-7-15(12)28;1-5(2,3)4/h4,6,8,11,17,21H,2-3,5,7,9-10H2,1H3,(H3-,24,25,26,30,32,33);(H2,1,2,3,4)/b27-16-;/t17-,21-;/m1./s1
InChi Key
KYOHRXSGUROPGY-OFNLCGNNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

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    Cayman Chemical
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    Product Description

    Cefquinome is a broad-spectrum cephalosporin antibiotic.1 It is active against clinical isolates of various Gram-positive and Gram-negative bacteria, including Salmonella, E. coli, and methicillin-resistant S. aureus (MRSA; MICs = 0.06-0.5, 0.015-0.5, and 1-16 µg/ml, respectively). Intramammary administration of cefquinome (75 mg/animal) is curative in a bovine model of E. coli-induced mastitis.2 Formulations containing cefquinome have been used in the treatment of coliform mastitis in veterinary medicine.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chin, N.-X., Gu, J.-W., Fang, W., et al. In vitro activity of cefquinome, a new cephalosporin, compared with other cephalosporin antibiotics. Diagn. Microbiol. Infect. Dis. 15(4), 331-337 (1992).

    2. Shpigel, N.Y., Levin, D., Winkler, M., et al. Efficacy of cefquinome for treatment of cows with mastitis experimentally induced using Escherichia coli. J. Dairy Sci. 80(2), 318-323 (1996).