An internal standard for the quantification of mitoquinol
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Mitoquinol-d15 (mesylate)

Item No. 34310

Technical Information
Formal Name
[10-(2,5-dihydroxy-3,4-dimethoxy-6-methylphenyl)decyl]triphenyl-d5-phosphonium, monomethanesulfonate
Molecular Formula
C37H31D15O4P • CH3O3S
Formula Weight
Purity
≥99% deuterated forms (d1-d15)
A solid
Chloroform: Slightly solubleDMSO: Slightly soluble
SMILES
O=S(C)([O-])=O.OC1=C(CCCCCCCCCC[P+](C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])C(C)=C(O)C(OC)=C1OC
InChi Code
InChI=1S/C37H45O4P.CH4O3S/c1-29-33(35(39)37(41-3)36(40-2)34(29)38)27-19-8-6-4-5-7-9-20-28-42(30-21-13-10-14-22-30,31-23-15-11-16-24-31)32-25-17-12-18-26-32;1-5(2,3)4/h10-18,21-26H,4-9,19-20,27-28H2,1-3H3,(H-,38,39);1H3,(H,2,3,4)/i10D,11D,12D,13D,14D,15D,16D,17D,18D,21D,22D,23D,24D,25D,26D;
InChi Key
WPMXVYGZUOSRAN-DBFLYWEVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    Mitoquinol-d15 is intended for use as an internal standard for the quantification of mitoquinol by GC- or LC-MS. Mitoquinol is a mitochondria-targeted antioxidant and reduced form of mitoquinone.1 It reduces hydrogen peroxide production in succinate-fueled isolated bovine aortic endothelial mitochondria.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kelso, G.F., Porteous, C.M., Coulter, C.V., et alSelective targeting of a redox-active ubiquinone to mitochondria within cells. Antioxidant and antiapoptotic properties. The Journal of Biological Chemisty 276(7), 4588-4596 (2001).

    2. O'Malley, Y., Fink, B.D., Ross, N.C., et alReactive oxygen and targeted antioxidant administration in endothelial cell mitochondria. The Journal of Biological Chemisty 281(52), 39766-39775 (2006).