A triterpene with ACE inhibitory activity
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Isomer(s)
33241Ganoderic Acid C6
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Ganoderic Acid N

Item No. 34323

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7β,20ξ-dihydroxy-3,11,15,23-tetraoxo-lanost-8-en-26-oic acid
CAS Number
110241-19-5
Molecular Formula
C30H42O8
Formula Weight
530.7
Purity
≥85%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
252 nm
SMILES
CC1(C)C(CC[C@]2(C)C3=C([C@@]4(C(C[C@@H]([C@]4(CC3=O)C)C(C)(O)CC(CC(C)C(O)=O)=O)=O)C)[C@@H](O)C[C@@]12[H])=O
InChi Code
InChI=1S/C30H42O8/c1-15(25(36)37)10-16(31)13-29(6,38)20-12-22(35)30(7)24-17(32)11-19-26(2,3)21(34)8-9-27(19,4)23(24)18(33)14-28(20,30)5/h15,17,19-20,32,38H,8-14H2,1-7H3,(H,36,37)/t15?,17-,19-,20-,27-,28+,29?,30-/m0/s1
InChi Key
XXHBQOHASACCAP-QNYQZGHFSA-N
Origin
Fungus/Ganoderma lucidum
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Ganoderic acid N is a triterpene that has been found in G. lingzhi and has angiotensin-converting enzyme (ACE) inhibitory activity.1 It inhibits ACE in a cell-free assay (IC50 = 0.941 mM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hai-Bang, T., and Shimizu, K. Structure–activity relationship and inhibition pattern of reishi-derived (Ganoderma lingzhi) triterpenoids against angiotensin-converting enzyme. Phytochem. Lett. 12, 243-247 (2015).