A flavonoid glycoside and DNA topoisomerase I inhibitor
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Mauritianin

Item No. 34326

Technical Information
Formal Name
3-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→6)]-β-D-galactopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CAS Number
109008-28-8
Synonyms
  • Kaempferol 3-O-(2",6"-di-O-α-rhamnopyranosyl)-β-galactopyranoside
  • Kaempferol 3-O-{α-L-rhamnopyranosyl(1→6)-[α-L-rhamnopyranosyl-(1→2)]}-β-D-galactopyranoside
Molecular Formula
C33H40O19
Formula Weight
Purity
≥95%
Formulation
A solid
λmax
267, 347 nm
SMILES
O=C(C(O[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)O)O)O[C@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O)O)O)=C(C4=CC=C(C=C4)O)OC5=CC(O)=C6)C5=C6O
InChi Code
InChI=1S/C33H40O19/c1-10-19(37)23(41)26(44)31(47-10)46-9-17-21(39)25(43)30(52-32-27(45)24(42)20(38)11(2)48-32)33(50-17)51-29-22(40)18-15(36)7-14(35)8-16(18)49-28(29)12-3-5-13(34)6-4-12/h3-8,10-11,17,19-21,23-27,30-39,41-45H,9H2,1-2H3/t10-,11-,17+,19-,20-,21-,23+,24+,25-,26+,27+,30+,31+,32-,33-/m0/s1
InChi Key
WRXVPTMENPZUIZ-MOVIZTNPSA-N
Origin
Plant/Hypericum japonicum
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Mauritianin is a flavonoid glycoside that has been found in R. anguifera and is a DNA topoisomerase I inhibitor.1 It stabilizes the covalent complex between DNA and recombinant human topoisomerase I when used at a concentration of 100 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ma, J., Jones, S.H., Marshall, R.A., et alDNA topoisomerase I inhibitors from Rinorea anguifera. Bioorg. Med. Chem. Lett. 15(3), 813-816 (2005).