A potential impurity found in commercial preparations of lacosamide
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O-Desmethyl Lacosamide

Item No. 34403

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2R-(acetylamino)-3-hydroxy-N-(phenylmethyl)-propanamide
CAS Number
175481-38-6
Molecular Formula
C12H16N2O3
Formula Weight
236.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleEthanol: Soluble
SMILES
O=C(NCC1=CC=CC=C1)[C@@H](CO)NC(C)=O
InChi Code
InChI=1S/C12H16N2O3/c1-9(16)14-11(8-15)12(17)13-7-10-5-3-2-4-6-10/h2-6,11,15H,7-8H2,1H3,(H,13,17)(H,14,16)/t11-/m1/s1
InChi Key
XRKSCJLQKGLSKU-LLVKDONJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $43

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    5 mg

    $118

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    10 mg

    $211

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    25 mg

    $475

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    Product Description

    O-Desmethyl lacosamide is a potential impurity found in commercial preparations of lacosamide.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Molleti, S., Rao, V., and Jayaveera, K.N. Stability indicating RP-UPLC method for the determination of lacosamide and its impurities in bulk drugs and its pharmaceutical dosage forms. Der Pharma Chemica 5(1), 81-89 (2013).

    2. Yang, A., Hu, F., Chen, M., et al. Improved synthesis and impurity identification of (R)-lacosamide. Org. Proc. Res. Dev. 23(5), 818-824 (2019).