A synthetic nonapeptide sedative
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Emideltide (acetate)

Item No. 34426

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Delta Sleep-inducing Peptide
  • DSIP
Molecular Formula
C35H48N10O15 • XC2H4O2
Formula Weight
848.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: slightly solublePBS (pH 7.2): 10 mg/ml
λmax
221 nm
SMILES
OC(CC[C@@H](C(O)=O)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H](CC(O)=O)NC(CNC(CNC([C@H](C)NC([C@@H](N)CC1=CNC2=CC=CC=C12)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O
InChi Code
InChI=1S/C35H48N10O15.C2H4O2/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51;1-2(3)4/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60);1H3,(H,3,4)/t16-,17-,20-,22-,23-,24-;/m0./s1
InChi Key
PMAPMBRAJAMLEE-BMMXBKKXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    5 mg

    $36

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    10 mg

    $63

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    25 mg

    $135

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    50 mg

    $236

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    Product Description

    Emideltide, also known as delta sleep-inducing peptide (DSIP), is a synthetic nonapeptide sedative.1 In vivo, emideltide (30 nmol/kg, i.v.) increases EEG delta activity and induces orthodox slow-wave sleep in free-moving rabbits. It also increases non-rapid eye movement (NREM) and total sleep in free-moving rats.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Monnier, M., Dudler, L., Gächter, R., et al. Delta sleep-inducing peptide (DSIP): EEG and motor activity in rabbits following intravenous administration. Neurosci. Lett. 6(1), 9-13 (1977).

    2. Kafi, S., Monnier, M., and Gallard, J.M. The delta-sleep inducing peptide (DSIP) increases duration of sleep in rats. Neurosci. Lett. 13(2), 169-172 (1979).