An active metabolite of phosphatidylethanolamine
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Glycerophosphorylethanolamine (sodium salt)

Item No. 34460

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
phosphoric acid, mono(2-aminoethyl) mono(2,3-dihydroxypropyl) ester, monosodium salt
CAS Number
883288-78-6
Synonyms
  • Glycerol 3-phosphorylethanolamine
  • Glycerylphosphorylethanolamine
Molecular Formula
C5H13NO6P • Na
Formula Weight
237.1
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: slightly soluble
SMILES
O=P(OCCN)(OCC(CO)O)[O-].[Na+]
InChi Code
InChI=1S/C5H14NO6P.Na/c6-1-2-11-13(9,10)12-4-5(8)3-7;/h5,7-8H,1-4,6H2,(H,9,10);/q;+1/p-1
InChi Key
LMVDUYIAODUIQA-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $267

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    Product Description

    Glycerophosphorylethanolamine is an active phosphodiester metabolite of phosphatidylethanolamine.1,2 It promotes aggregation of amyloid-β (1-40) (Aβ40) in vitro, and levels of glycerophosphorylethanolamine are elevated in postmortem brains isolated from patients with Alzheimer's disease.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Klunk, W.E., Xu, C.J., McClure, R.J., et al. Aggregation of β-amyloid peptide is promoted by membrane phospholipid metabolites elevated in Alzheimer’s disease brain. J. Neurochem. 69(1), 266-272 (1997).

    2. Blusztajn, J.K., Lopez Gonzalez-Coviella, I., Logue, M., et al. Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer’s disease but not of Down’s syndrome patients. Brain Res. 536(1-2), 240-244 (1990).