A methylated purine nucleoside
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

1-Methylinosine

Item No. 34461

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
2140-73-0
Synonyms
  • 1-methyl Inosine
  • N1-Methylinosine
Molecular Formula
C11H14N4O5
Formula Weight
282.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 15 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
252 nm
SMILES
O[C@H]1[C@](O[C@@H]([C@H]1O)CO)([H])N2C3=C(C(N(C=N3)C)=O)N=C2
InChi Code
InChI=1S/C11H14N4O5/c1-14-3-13-9-6(10(14)19)12-4-15(9)11-8(18)7(17)5(2-16)20-11/h3-5,7-8,11,16-18H,2H2,1H3/t5-,7-,8-,11-/m1/s1
InChi Key
WJNGQIYEQLPJMN-IOSLPCCCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    100 mg

    $230

    Add

    250 mg

    $543

    Add

    500 mg

    $1,030

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    1-Methylinosine is a methylated purine nucleoside formed during the degradation of tRNA.1 Urinary levels of 1-methylinosine are increased in patients with acute myelomonocytic leukemia or large cell lung carcinoma. Urinary levels are also increased in patients with breast cancer and are associated with a reduced five-year survival rate.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mitchell, E.P., Evans, L., Schultz, P., et al. Modified nucleosides in human serum. J. Chromatogr. 581(1), 31-40 (1992).

    2. Sasco, A.J., Rey, F.A., Reynaud, C., et al. Breast cancer prognostic significance of some modified urinary nucleosides. Cancer Lett. 108(2), 157-162 (1996).