A thiol-reactive fluorogenic probe
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7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt)

Item No. 34564

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid, monoammonium salt
CAS Number
84806-27-9
Synonyms
  • Ammonium 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonate
  • 7-Fluorobenzofurazan-4-Sulfonic Acid
  • SBD-F
Molecular Formula
C6H2FN2O4S • NH4
Formula Weight
235.2
Purity
≥98%
Emission
515 nm
Excitation
380 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
316 nm
SMILES
O=S([O-])(C1=CC=C(C2=NON=C21)F)=O.[NH4+]
InChi Code
InChI=1S/C6H3FN2O4S.H3N/c7-3-1-2-4(14(10,11)12)6-5(3)8-13-9-6;/h1-2H,(H,10,11,12);1H3
InChi Key
JXLHNMVSKXFWAO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $131

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    50 mg

    $236

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    100 mg

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    250 mg

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    Product Description

    7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F) is a thiol-reactive fluorogenic probe.1 It has been used to quantify the levels of homocysteine, cysteine, and cysteamine in human plasma.2 SBD-F displays excitation/emission maxima of 380/515 nm, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Imai, K., Toyo'oka, T., and Watanabe, Y. A novel fluorogenic reagent for thiols: Ammonium 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonate. Anal. Biochem. 128(2), 471-473 (1983).

    2. Ichinose, S., Nakamura, M., Maeda, M., et al. A validated HPLC-fluorescence method with a semi-micro column for routine determination of homocysteine, cysteine and cysteamine, and the relation between the thiol derivatives in normal human plasma. Biomed. Chromatogr. 23(9), 935-939 (2009).