An intermediate in the catabolism of L-tryptophan, L-lysine, and hydroxylysine
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2-Oxoadipic Acid

Item No. 34574

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-oxo-hexanedioic acid
CAS Number
3184-35-8
Synonyms
  • α-Ketoadipate
  • 2-Ketoadipic Acid
  • α-Ketoadipic Acid
  • α-Oxoadipic Acid
Molecular Formula
C6H8O5
Formula Weight
160.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 250 mg/ml, sonicated
SMILES
O=C(C(CCCC(O)=O)=O)O
InChi Code
InChI=1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)
InChi Key
FGSBNBBHOZHUBO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $36

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    10 mg

    $68

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    25 mg

    $153

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    50 mg

    $288

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    Product Description

    2-Oxoadipic acid is an intermediate in the catabolism of L-tryptophan, L-lysine, and hydroxylysine.1,2 Urinary excretion of 2-oxoadipic acid is increased in patients with α-ketoadipic aciduria, a rare inborn error in the metabolism of 2-oxoadipic acid to glutaryl-coenzyme A (glutaryl-CoA).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Xia, Z.-W., Inoue, Y., Ohse, M., et al. A study on α-ketoadipic aciduria by gas chromatographic-mass spectrometry. World J. Gastroenterol. 6(5), 766-769 (2000).

    2. Gray, R.G., O'Neill, E.M., and Pollitt, R.J. α-aminoadipic aciduria: Chemical and enzymatic studies. J. Inherit. Metab. Dis. 2(4), 89-92 (1980).