A triterpene saponin with diverse biological activities
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Ardisiacrispin A

Item No. 34615

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,16α,20β)-13,28-epoxy-3-[(O-β-D-glucopyranosyl-(1→2)-O-[O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl)oxy]-16-hydroxy-oleanan-29-al
CAS Number
23643-61-0
Synonyms
  • Deglucocyclamin
  • LTS-4
  • Saxifragifolin B
Molecular Formula
C52H84O22
Formula Weight
1061.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: soluble
SMILES
C[C@]12[C@]3(CC[C@@]4([H])[C@]2(CC[C@]5([H])[C@@]4(CC[C@@H](C5(C)C)O[C@H]6[C@@H]([C@H]([C@H](CO6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O)O)O)CO)C)C)[C@@]%10([H])[C@@]([C@@H](C1)O)(CC[C@@](C)(C%10)C=O)CO3
InChi Code
InChI=1S/C52H84O22/c1-46(2)27-7-11-49(5)28(8-12-52-29-15-47(3,21-55)13-14-51(29,22-68-52)30(57)16-50(49,52)6)48(27,4)10-9-31(46)72-44-40(74-43-39(65)36(62)33(59)24(17-53)69-43)35(61)26(20-67-44)71-45-41(37(63)34(60)25(18-54)70-45)73-42-38(64)32(58)23(56)19-66-42/h21,23-45,53-54,56-65H,7-20,22H2,1-6H3/t23-,24-,25-,26+,27+,28-,29-,30-,31+,32+,33-,34-,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,47+,48+,49-,50+,51-,52+/m1/s1
InChi Key
JXTOWLUQSHIIDP-VKKSEJOZSA-N
Origin
Plant/Unspecified sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Ardisiacrispin A is a triterpene saponin that has been found in Myrsine australis and has diverse biological activities.1,2,3 It inhibits the cytopathic effects of poliovirus type I and herpes simplex virus 1 (HSV-1) in the filter paper disk assay when used at a concentration of 40 µg/disk and is active against various Candida species (MICs = 80-160 µg/ml).1,2 Ardisiacrispin A (10 and 13 µM) induces apoptosis in HepG2 cells.3 It induces contractions in rat uterus preparations when used at a concentration of 7.5 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bloor, S.J., and Qi, L. Cytotoxic saponins from New Zealand Myrsine species. J. Nat. Prod. 57(10), 1354-1360 (1994).

    2. Çaliş, İ., Şatana, M.E., Yürüker, A., et al. Triterpene saponins from Cyclamen mirabile and their biological activities. J. Nat. Prod. 60(3), 315-318 (1997).

    3. Zhang, D.-M., Wang, Y., Tang, M.-K., et al. Saxifragifolin B from Androsace umbellata induced apoptosis on human hepatoma cells. Biochem. Biophys. Res. Commun. 362(3), 759-765 (2007).