A glycine-conjugated form of suberic acid
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Suberylglycine

Item No. 34619

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8-[(carboxymethyl)amino]-8-oxo-octanoic acid
CAS Number
60317-54-6
Molecular Formula
C10H17NO5
Formula Weight
231.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: slightly solubleMethanol: slightly soluble
SMILES
O=C(CNC(CCCCCCC(O)=O)=O)O
InChi Code
InChI=1S/C10H17NO5/c12-8(11-7-10(15)16)5-3-1-2-4-6-9(13)14/h1-7H2,(H,11,12)(H,13,14)(H,15,16)
InChi Key
HXATVKDSYDWTCX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $54

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    25 mg

    $106

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    50 mg

    $197

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    100 mg

    $367

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    Product Description

    Suberylglycine is a glycine-conjugated form of the dicarboxylic acid suberic acid.1 Urinary levels of suberylglycine are increased in patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.2,3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Truscott, R.J., Hick, L., Pullin, C., et al. Dicarboxylic aciduria: The response to fasting. Clin. Chim. Acta 94(1), 31-39 (1979).

    2. Bhuiyan, A.K., Watmough, N.J., Turnbull, D.M., et al. A new simple screening method for the diagnosis of medium chain acyl-CoA dehydrogenase deficiency. Clin. Chim. Acta 165(1), 39-44 (1987).

    3. Onkenhout, W., Venizelos, V., van der Poel, P.F.H., et al. Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. Clin. Chem. 41(10), 1467-1474 (1995).

    4. Rinaldo, P., O'Shea, J.J., Coates, P.M., et al. Medium-chain acyl-CoA dehydrogenase deficiency. Diagnosis by stable-isotope dilution measurement of urinary n-hexanoylglycine and 3-phenylpropionylglycine. N. Engl. J. Med. 319(20), 1308-1313 (1988).