A triterpenoid with anticancer and anti-inflammatory activities
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Ganoderic Acid G

Item No. 34675

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3β,7β,12β-trihydroxy-11,15,23-trioxo-lanost-8-en-26-oic acid
CAS Number
98665-22-6
Molecular Formula
C30H44O8
Formula Weight
532.7
Purity
≥95% (mixture of isomers)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
252 nm
SMILES
O=C(C(CC(CC(C1CC(C2(C)C3=C(C4(CC[C@@H](C(C)(C4C[C@@H]3O)C)O)C)C([C@H](C12C)O)=O)=O)C)=O)C)O
InChi Code
InChI=1S/C30H44O8/c1-14(10-16(31)11-15(2)26(37)38)17-12-21(34)30(7)22-18(32)13-19-27(3,4)20(33)8-9-28(19,5)23(22)24(35)25(36)29(17,30)6/h14-15,17-20,25,32-33,36H,8-13H2,1-7H3,(H,37,38)/t14?,15?,17?,18-,19?,20-,25+,28?,29?,30?/m0/s1
InChi Key
BPJPBLZKOVIJQD-ODGZWCFJSA-N
Origin
Fungus/Ganoderma lucidum
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $69

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    5 mg

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    10 mg

    $427

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    25 mg

    $983

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    Product Description

    Ganoderic acid G is a triterpenoid that has been found in G. lucidum and has anticancer and anti-inflammatory activities.1,2 It inhibits the proliferation of Meth A sarcoma cells (IC50 = 6.8 µg/ml).1 Ganoderic acid G inhibits the production of nitric oxide (NO) in LPS-induced BV-2 microglial cells (IC50 = 5.77 µM).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Min, B.S., Gao, J.J., Nakamura, N., et al. Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells. Chem. Pharm. Bull. (Tokyo) 48(7), 1026-1033 (2000).

    2. Yang, J., Ting, X., Zou, L.-H., et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg. Med. Chem. Lett. 26(15), 3556-3561 (2018).