A synthetic bioluminescent luciferin
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Coelenterazine hcp

Item No. 34724

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8-(cyclopentylmethyl)-6-(4-hydroxyphenyl)-2-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one
CAS Number
123437-32-1
Molecular Formula
C25H25N3O2
Formula Weight
399.5
Purity
≥90%
Emission
445 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: soluble
SMILES
O=C1C(CC2=CC=CC=C2)=NC3=C(CC4CCCC4)NC(C5=CC=C(O)C=C5)=CN13
InChi Code
InChI=1S/C25H25N3O2/c29-20-12-10-19(11-13-20)23-16-28-24(21(26-23)14-17-8-4-5-9-17)27-22(25(28)30)15-18-6-2-1-3-7-18/h1-3,6-7,10-13,16-17,26,29H,4-5,8-9,14-15H2
InChi Key
YEGCUOQUFAXCMK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 µg

    $134

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    Product Description

    Coelenterazine hcp is a synthetic bioluminescent luciferin that displays an emission maximum of 445 nm.1 It has been used as a calcium indicator and substrate to quantify Renilla luciferase activity.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010).

    2. Shimomura, O., Kishi, Y., and Inouye, S. The relative rate of aequorin regeneration from apoaequorin and coelenterazine analogues. Biochem. J. 296(Pt 3), 549-551 (1993).

    3. Pichler, A., Prior, J.L., and Piwnica-Worms, D. Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine. Proc. Natl. Acad. Sci. USA 101(6), 1702-1707 (2004).