A metabolite of sulforaphane
Related Products
Active Metabolite(s)
39555S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine
Parent Compound(s)
10496Sulforaphane
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DL-Sulforaphane Glutathione

Item No. 34731

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-γ-glutamyl-S-[[[4-(methylsulfinyl)butyl]amino]thioxomethyl]-L-cysteinyl-glycine
CAS Number
289711-21-3
Synonyms
  • SFN-glutathione
  • SFN-GSH
  • Sulforaphane-GSH
Molecular Formula
C16H28N4O7S3
Formula Weight
484.6
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: soluble upon heatingWater: soluble
λmax
253 nm
SMILES
OC([C@@H](N)CCC(N[C@@H](CSC(NCCCCS(C)=O)=S)C(NCC(O)=O)=O)=O)=O
InChi Code
InChI=1S/C16H28N4O7S3/c1-30(27)7-3-2-6-18-16(28)29-9-11(14(24)19-8-13(22)23)20-12(21)5-4-10(17)15(25)26/h10-11H,2-9,17H2,1H3,(H,18,28)(H,19,24)(H,20,21)(H,22,23)(H,25,26)/t10-,11-,30?/m0/s1
InChi Key
ROARKYNVUQLTDP-QGQIPBJJSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $37

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    5 mg

    $145

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    10 mg

    $270

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    25 mg

    $629

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    Product Description

    DL-Sulforaphane glutathione is a metabolite of the class I and II histone deacetylase (HDAC) inhibitor and anticancer agent sulforaphane (Item No. 10496).1 It increases mRNA expression of the genes encoding glutathione S-transferase A1 (GSTA1) and the UDP-glucuronosyltransferase (UGT) isoform UGT1A1 in HepG2 cells when used at a concentration of 15 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, H., Khor, T.O., Yang, Q., et al. Pharmacokinetics and pharmacodynamics of phase II drug metabolizing/antioxidant enzymes gene response by anticancer agent sulforaphane in rat lymphocytes. Mol. Pharmacol. 9(10), 2819-2827 (2012).

    2. Basten, G.P., Bao, Y., and Williamson, G. Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells. Carcinogenesis 23(8), 1399-1404 (2002).