A synthetic intermediate
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N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 2-ethylbutyl ester

Item No. 34748

Technical Information
CAS Number
1354823-36-1
Molecular Formula
C21H27N2O7P
Formula Weight
Purity
≥98%
A solid
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 25 mg/ml
λmax
270 nm
SMILES
CCC(CC)COC([C@H](C)N[P@@](OC1=CC=C(C=C1)[N+]([O-])=O)(OC2=CC=CC=C2)=O)=O
InChi Code
InChI=1S/C21H27N2O7P/c1-4-17(5-2)15-28-21(24)16(3)22-31(27,29-19-9-7-6-8-10-19)30-20-13-11-18(12-14-20)23(25)26/h6-14,16-17H,4-5,15H2,1-3H3,(H,22,27)/t16-,31-/m0/s1
InChi Key
CSURKLFFMMBEFL-ZYSBOAIWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 2-ethylbutyl ester is a synthetic intermediate.1 It has been used in the synthesis of remdesivir (Item No. 30354).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Warren, T.K., Jordan, R., Lo, M.K., et alTherapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys. Nature 531(7594), 381-385 (2016).