An alkaloid with cholinesterase inhibitory activity
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N-Nornuciferine (hydrochloride)

Item No. 34756

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5,6,6aR,7-tetrahydro-1,2-dimethoxy-4H-dibenzo[de,g]quinoline, monohydrochloride
CAS Number
58546-00-2
Synonyms
  • Daechualkaloid E
  • (R)-Nornuciferine
  • (–)-Nornuciferine
  • Sanjoinine Ia
Molecular Formula
C18H19NO2 • HCl
Formula Weight
317.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
λmax
232, 271 nm
SMILES
COC1=C2C3=C(C=C1OC)CCN[C@]3([H])CC4=CC=CC=C42.Cl
InChi Code
InChI=1S/C18H19NO2.ClH/c1-20-15-10-12-7-8-19-14-9-11-5-3-4-6-13(11)17(16(12)14)18(15)21-2;/h3-6,10,14,19H,7-9H2,1-2H3;1H/t14-;/m1./s1
InChi Key
RBJGEWHGFMPNFU-PFEQFJNWSA-N
Origin
Plant/Nelumbo nucifera
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $87

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    5 mg

    $218

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    10 mg

    $392

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    Product Description

    N-Nornuciferine is an alkaloid that has been found in A. grandifolia and has cholinesterase inhibitory activity.1 It is an inhibitor of butyrylcholinesterase (BChE; IC50 = 5.6 µM for the mouse enzyme).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cometa, M.F., Fortuna, S., Palazzino, G., et al. New cholinesterase inhibiting bisbenzylisoquinoline alkaloids from Abuta grandifolia. Fitoterapia 83(3), 476-480 (2012).