An intermediate in the synthesis of sildenafil
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Sildenafil Chlorosulfonyl

Item No. 34760

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxy-benzenesulfonyl chloride
CAS Number
139756-22-2
Synonyms
  • CMP
Molecular Formula
C17H19ClN4O4S
Formula Weight
410.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: 1 mg/mlDMSO: slightly soluble
λmax
273 nm
SMILES
O=C1N=C(C2=C(OCC)C=CC(S(=O)(Cl)=O)=C2)NC3=C1N(C)N=C3CCC
InChi Code
InChI=1S/C17H19ClN4O4S/c1-4-6-12-14-15(22(3)21-12)17(23)20-16(19-14)11-9-10(27(18,24)25)7-8-13(11)26-5-2/h7-9H,4-6H2,1-3H3,(H,19,20,23)
InChi Key
RVVOSOSBFSYZDM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $41

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    500 mg

    $69

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    1 g

    $103

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    5 g

    $351

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    Product Description

    Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor sildenafil (Item No. 10008671).1 It is also a potential impurity found in commercial preparations of sildenafil.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nagaraju, V., Sreenath, D., Rao, J.T., et al. Separation and determination of synthetic impurities of sildenafil (Viagra) by reversed-phase high-performance liquid chromatography. Anal. Sci. 19(7), 1007-1011 (2003).