An alkaloid with analgesic and anesthetic activities
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Product Categories

Product Type

Biochemicals
Natural Products
Alkaloids

Research Area

Neuroscience
Pain Research

Ranaconitine

Item No. 34774

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
20-ethyl-1α,14α,16β-trimethoxy-aconitane-4,7,8,9-tetrol 4-[2-(acetylamino)benzoate]
CAS Number
1360-76-5
Synonyms
  • 7-hydroxy Lappaconitine
Molecular Formula
C32H44N2O9
Formula Weight
600.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:4): 0.2 mg/mlDMSO: 10 mg/mlEthanol: 1 mg/ml
λmax
223, 252 nm
SMILES
CO[C@@H]1[C@@]23[C@@]4([H])[C@](C[C@@H]2[C@](CN4CC)(CC1)OC(C5=C(C=CC=C5)NC(C)=O)=O)([C@@]6([C@@]7([C@@]3([H])C[C@H]([C@H](C6)OC)[C@@H]7OC)O)O)O
InChi Code
InChI=1S/C32H44N2O9/c1-6-34-16-28(43-26(36)18-9-7-8-10-20(18)33-17(2)35)12-11-24(41-4)31-22-13-19-21(40-3)14-30(38,32(22,39)25(19)42-5)29(37,27(31)34)15-23(28)31/h7-10,19,21-25,27,37-39H,6,11-16H2,1-5H3,(H,33,35)/t19-,21+,22+,23-,24+,25+,27-,28-,29-,30+,31+,32+/m1/s1
InChi Key
XTSVKUJYTUPYRJ-VHXKHITRSA-N
Origin
Plant/Aconitum carmichaelii
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $36

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    5 mg

    $128

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    10 mg

    $236

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    25 mg

    $502

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    Product Description

    Ranaconitine is an alkaloid that has been found in Aconitum and has analgesic and local anesthetic activities in mice (ED50s = 6.99 and 0.167 µmol/kg, respectively).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bello-Ramírez, A.M., and Nava-Ocampo, A.A. A QSAR analysis of toxicity of Aconitum alkaloids. Fundam. Clin. Pharmacol. 18(6), 699-704 (2004).