An internal standard for the quantification of glycine
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Alternative(s)
35130Glycine-13C
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Glycine-d5

Item No. 34825

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
glycine-N,N,1,2,2-d5
CAS Number
4896-77-9
Synonyms
  • Aminoacetic Acid-d5
Molecular Formula
C2D5NO2
Formula Weight
80.1
Purity
≥99% deuterated forms (d1-d5)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: 1 mg/mlPBS (pH 7.2): 1 mg/ml
SMILES
[2H]N([2H])C([2H])([2H])C(O[2H])=O
InChi Code
InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)/i1D2/hD3
InChi Key
DHMQDGOQFOQNFH-LGLHGEJLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $32

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    100 mg

    $141

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    500 mg

    $542

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    Product Description

    Glycine-d5 is intended for use as an internal standard for the quantification of glycine by GC- or LC-MS. Glycine is a conditionally essential amino acid and the major inhibitory neurotransmitter in the spinal cord and brainstem.1,2 It is synthesized from threonine, choline, hydroxyproline, and serine via interorgan metabolism between the liver and kidneys.2 It can also be derived from dietary sources. Glycine is essential to protein synthesis and the conjugation of bile acids and is a precursor in glutathione, purine, heme, and serine synthesis.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zafra, F., Aragón, C., Olivares, L., et al. Glycine transporters are differentially expressed among CNS cells. J. Neurosci. 15(5 Pt 2), 3952-3969 (1995).

    2. Wang, W., Wu, Z., Dai, Z., et al. Glycine metabolism in animals and humans: Implications for nutrition and health. Amino Acids 45(3), 463-477 (2013).