An internal standard for the quantification of L-threonine
Related Products
Unlabeled Version(s)
30194L-Threonine
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L-Threonine-d2

Item No. 34828

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-threonine-2,3-d2
CAS Number
1202936-45-5
Synonyms
  • (S)-Threonine-d2
Molecular Formula
C4H7D2NO3
Formula Weight
121.1
Purity
≥99% deuterated forms (d1-d2)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 2 mg/ml
SMILES
C[C@](O)([2H])[C@@](N)([2H])C(O)=O
InChi Code
InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1/i2D,3D
InChi Key
AYFVYJQAPQTCCC-JZFQEKCDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $69

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    5 mg

    $263

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    10 mg

    $493

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    25 mg

    $1,062

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    Product Description

    L-Threonine-d2 is intended for use as an internal standard for the quantification of L-threonine (Item No. 30194) by GC- or LC-MS. L-Threonine is an essential amino acid.1 It undergoes catabolism via threonine dehydrogenase to yield the glucogenic metabolites succinyl coenzyme A (succinyl CoA) and pyruvate. Administration of L-threonine-deficient diets induces lameness of the thoracic and pelvic limbs and decreases food intake and weight gain in kittens.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Massey, K.A., Blakeslee, C.H., and Pitkow, H.S. A review of physiological and metabolic effects of essential amino acids. Amino Acids 14(4), 271-300 (1998).

    2. Titchenal, C.A., Rogers, Q.R., Indrieri, R.J., et al. Threonine imbalance, deficiency and neurologic dysfunction in the kitten. J. Nutr. 110(12), 2444-2459 (1980).