A near-infrared fluorescent dye
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Product Categories

Product Type

Biochemicals
Labeling & Detection
Fluorescent Probes

Research Area

Cancer

Application

Fluorescence

1,1-Dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine (iodide)

Item No. 34954

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[7-(1,3-dihydro-3,3-dimethyl-1-octadecyl-2H-indol-2-ylidene)-1,3,5-heptatrien-1-yl]-3,3-dimethyl-1-octadecyl-3H-indolium, monoiodide
CAS Number
100068-60-8
Synonyms
  • DiR
Molecular Formula
C63H101N2 • I
Formula Weight
1013.4
Purity
≥98%
Emission
780 nm
Excitation
750 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: Slightly SolubleDMSO: Slightly SolubleEthanol: 1 mg/mL
λmax
748 nm
SMILES
CC1(C)C2=C(C=CC=C2)N(CCCCCCCCCCCCCCCCCC)C1=CC=CC=CC=CC3=[N+](CCCCCCCCCCCCCCCCCC)C4=C(C3(C)C)C=CC=C4.[I-]
InChi Code
InChI=1S/C63H101N2.HI/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38-46-54-64-58-50-44-42-48-56(58)62(3,4)60(64)52-40-36-35-37-41-53-61-63(5,6)57-49-43-45-51-59(57)65(61)55-47-39-34-32-30-28-26-24-22-20-18-16-14-12-10-8-2;/h35-37,40-45,48-53H,7-34,38-39,46-47,54-55H2,1-6H3;1H/q+1;/p-1
InChi Key
JLIOTPLALDYAEH-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    Product Description

    1,1-Dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine (DiR) is a lipophilic near-infrared fluorescent dye.1 It displays excitation/emission maxima of 750/780 nm, respectively. DiR has been incorporated into PEGylated nanoparticles for use in antitumor photothermal therapy in mice.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wagh, A., Qian, S.Y., and Law, B. Development of biocompatible polymeric nanoparticles for in vivo NIR and FRET imaging. Bioconjug. Chem. 23(5), 981-992 (2012).

    2. Zhang, X., Sun, B., Zuo, S., et al. Self-assembly of a pure photosensitizer as a versatile theragnostic nanoplatform for imaging-guided antitumor photothermal therapy. ACS Appl. Mater. Interfaces 10(36), 30155-30162 (2018).