A nonpeptide substrate of proteases and deiminases
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N-α-Benzoyl-L-Argininamide (hydrochloride)

Item No. 35015

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(S)-N-[1-(aminocarbonyl)-4-[(aminoiminomethyl)amino]butyl]-benzamide, monohydrochloride
CAS Number
4299-03-0
Synonyms
  • BAA
  • Benzoylarginamide
  • Bz-Arg-NH2
  • NSC 343719
Molecular Formula
C13H19N5O2 • HCl
Formula Weight
313.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 2 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
227 nm
SMILES
N=C(N)NCCC[C@@H](C(N)=O)NC(C1=CC=CC=C1)=O.Cl
InChi Code
InChI=1S/C13H19N5O2.ClH/c14-11(19)10(7-4-8-17-13(15)16)18-12(20)9-5-2-1-3-6-9;/h1-3,5-6,10H,4,7-8H2,(H2,14,19)(H,18,20)(H4,15,16,17);1H/t10-;/m0./s1
InChi Key
PYZACNCNNFUUDO-PPHPATTJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $62

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    5 g

    $258

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    Product Description

    N-α-Benzoyl-L-argininamide is a nonpeptide substrate of proteases and deiminases.1,2,3 It has been used as a substrate for the quantification of papain, carboxypeptidase B, protein arginine deiminase 2 (PAD2), and PAD4 activities.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Whitaker, J.R., and Bender, M.L. Kinetics of papain-catalyzed hydrolysis of α-N-Benzoyl-L-arginine ethyl ester and α-N-Benzoyl-L-argininamide. J. Am. Chem. Soc. 87(12), 2728-2737 (1965).

    2. Monsalve, M., Wu, Z., Adelmant, G., et al. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol. Cell 6, 307-316 (2000).

    3. Nakayama-Hamada, M., Suzuki, A., Kubota, K., et al. Comparison of enzymatic properties between hPADI2 and hPADI4. Biochem. Biophys. Res. COmmun. 327(1), 192-200 (2005).