An inactive metabolite of topiramate
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Parent Compound(s)
13623Topiramate
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4,5-Desisopropylidene Topiramate

Item No. 35071

Technical Information
Formal Name
2,3-O-(1-methylethylidene)-β-D-fructopyranose 1-sulfamate
CAS Number
106881-41-8
Synonyms
  • 4,5-Desisopropylidene TPM
Molecular Formula
C9H17NO8S
Formula Weight
Purity
≥95%
A solid
Methanol: slightly, sonicatedWater: slightly, heated
SMILES
NS(OC[C@@]12[C@@]([C@@H]([C@@H](CO2)O)O)([H])OC(C)(O1)C)(=O)=O
InChi Code
InChI=1S/C9H17NO8S/c1-8(2)17-7-6(12)5(11)3-15-9(7,18-8)4-16-19(10,13)14/h5-7,11-12H,3-4H2,1-2H3,(H2,10,13,14)/t5-,6-,7+,9+/m1/s1
InChi Key
CKFVNUZYZFRVCR-JAKMQLQISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    4,5-Desisopropylidene topiramate is an inactive metabolite of the anticonvulsant topiramate.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Maryanoff, B.E., Nortey, S.O., Gardocki, J.F., et alAnticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate and related compounds. J. Med. Chem. 30(5), 880-887 (1987).

    2. Milosheska, D. A novel LC-MS/MS method for the simultaneous quantification of topiramate and its main metabolites in human plasma. J. Pharm. Biomed. Anal. 138, 180-188 (2017).