A coccidiostat
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Nicarbazine

Item No. 35110

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N′-bis(4-nitrophenyl)-urea, compd. with 4,6-dimethyl-2(1H)-pyrimidinone
CAS Number
330-95-0
Synonyms
  • MK 75
  • NCZ
  • NSC 7171
  • Nicarbazin
Molecular Formula
C13H10N4O5 • C6H8N2O
Formula Weight
426.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly soluble
λmax
222, 341 nm
SMILES
O=C1N=C(C)C=C(C)N1.O=C(NC2=CC=C([N+]([O-])=O)C=C2)NC3=CC=C([N+]([O-])=O)C=C3
InChi Code
InChI=1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9)
InChi Key
UKHWDRMMMYWSFL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Nicarbazine is a coccidiostat.1 It is composed of an equimolar complex of 4,4'-dinitrocarbanilide (DNC) and 2-hydroxy-4,6-dimethylpyrimidine (HDP). Nicarbazine (0.01-0.04% in the diet) prevents mortality of, and suppresses oocyst production in, chickens infected with the parasites E. acervulina, E. necatrix, E. tenella, and P. gallinaceum. Dietary administration of nicarbazine (100 ppm) decreases the production, weight, and pigmentation of eggs produced by broiler breeder chickens.2 Formulations containing nicarbazine have been used in the prevention of coccidiosis in chickens.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ott, W.H., Kuna, S., Porter, C.C., et al. Biological studies on nicarbazin, a new anticoccidial agent. Poult. Sci. 35(6), 1355-1367 (1956).

    2. Hughes, B.L., Jones, J.E., and Toler, J.E. Effects of exposing broiler breeders to nicarbazin contaminated feed. Poult. Sci. 70(3), 476-482 (1991).