A typical antipsychotic
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Piperacetazine

Item No. 35220

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[10-[3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl]-10H-phenothiazin-2-yl]-ethanone
CAS Number
3819-00-9
Synonyms
  • PC-1421
  • SC-9794
Molecular Formula
C24H30N2O2S
Formula Weight
410.6
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 11 mg/mlDMSO: 10 mg/mlEthanol: Slightly solublePBS (pH 7.2): 0.30 mg/ml
λmax
244, 279 nm
SMILES
O=C(C)C1=CC=C2SC3=CC=CC=C3N(CCCN4CCC(CC4)CCO)C2=C1
InChi Code
InChI=1S/C24H30N2O2S/c1-18(28)20-7-8-24-22(17-20)26(21-5-2-3-6-23(21)29-24)13-4-12-25-14-9-19(10-15-25)11-16-27/h2-3,5-8,17,19,27H,4,9-16H2,1H3
InChi Key
BTFMCMVEUCGQDX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    Cayman Chemical
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    Product Description

    Piperacetazine is a typical antipsychotic.1 It inhibits spontaneous motor activity and responding for food in rats, as well as potentiates hexobarbital-induced narcosis in mice. It also inhibits lysosome acidification, as well as viral entry (IC50 = <8.5 µM), in Ebola-infected Huh7 cells.2 Formulations containing piperacetazine have been used in the treatment of schizophrenia.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pitman-Moore Piperacetazine (Quide tablets). Clin. Pharmacol. Ther. 10(5), 749-754 (1969).

    2. Dyall, J., Nelson, E.A., DeWald, L.E., et al. Identification of combinations of approved drugs with synergistic activity against Ebola virus in cell cultures. J. Infect. Dis. 218(Suppl 5), S672-S678 (2018).