An active metabolite of DHEA
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5-Androstenetriol

Item No. 35273

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
androst-5-ene-3β,16α,17β-triol
CAS Number
4150-30-5
Synonyms
  • Δ5-AT
Molecular Formula
C19H30O3
Formula Weight
306.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleEthanol: soluble
SMILES
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)([C@H]([C@@H](C4)O)O)C
InChi Code
InChI=1S/C19H30O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h3,12-17,20-22H,4-10H2,1-2H3/t12-,13+,14-,15-,16+,17-,18-,19-/m0/s1
InChi Key
GUGSXATYPSGVAY-DHKQUUGRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $82

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    5 mg

    $363

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    10 mg

    $643

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    Product Description

    5-Androstenetriol is a steroid and an active metabolite of dehydroepiandrosterone (DHEA; Item No. 15728).1 In vivo, 5-androstenetriol (0.75 mg/25 g body weight) reduces radiation-induced lethality and induces hematopoietic recovery from surviving stem cells in mice. It increases survival in a rat model of surgical trauma-induced sepsis when administered at a dose of 40 mg/kg.2 Urinary levels of 5-androstenetriol are increased in women with androgenic alopecia.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Loria, R.M., Conrad, D.H., Huff, T., et al. Androstenetriol and androstenediol. Protection against lethal radiation and restoration of immunity after radiation injury. Ann. N. Y. Acad. Sci. 917(1), 860-867 (2000).

    2. Marcu, A.C., Kielar, N.D., Paccione, K.E., et al. Androstenetriol improves survival in a rodent model of traumatic shock. Resuscitation 71(3), 379-386 (2006).

    3. Juricskay, S., and Telegdy, E. Urinary steroids in women with androgenic alopecia. Clin. Biochem. 33(2), 97-101 (2000).