A peptide DPP-4 inhibitor
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H-Gly-Pro-Hyp-OH (acetate)

Item No. 35390

Technical Information
Formal Name
glycyl-L-prolyl-4R-hydroxy-L-proline, monoacetate
CAS Number
103192-50-3
Synonyms
  • H-GP-Hyp-OH
  • Tripeptide-29
Molecular Formula
C12H19N3O5 • C2H4O2
Formula Weight
Purity
≥95%
Formulation
A solid
PBS (pH 7.2): 2 mg/ml
SMILES
NCC(N1CCC[C@H]1C(N2C[C@H](O)C[C@H]2C(O)=O)=O)=O.CC(O)=O
InChi Code
InChI=1S/C12H19N3O5.C2H4O2/c13-5-10(17)14-3-1-2-8(14)11(18)15-6-7(16)4-9(15)12(19)20;1-2(3)4/h7-9,16H,1-6,13H2,(H,19,20);1H3,(H,3,4)/t7-,8+,9+;/m1./s1
InChi Key
FXDGXPQAQHTCOM-KEMIKLHMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    H-Gly-Pro-Hyp-OH is a peptide dipeptidyl peptidase 4 (DPP-4) inhibitor (IC50 = 2.51 mM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hatanaka, T., Kawakami, K., and Uraji, M. Inhibitory effect of collagen-derived tripeptides on dipeptidylpeptidase-IV activity. J. Enzyme Inhib. Med. Chem. 29(6), 823-828 (2014).