An acetylated form of L-glutamine
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N-acetyl-L-Glutamine

Item No. 35398

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N2-acetyl-L-glutamine
CAS Number
2490-97-3
Synonyms
  • Aceglutamide
  • Acetylglutamine
  • N-acetyl Gln
  • NSC 186896
Molecular Formula
C7H12N2O4
Formula Weight
188.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 2 mg/ml
SMILES
NC(CC[C@H](NC(C)=O)C(O)=O)=O
InChi Code
InChI=1S/C7H12N2O4/c1-4(10)9-5(7(12)13)2-3-6(8)11/h5H,2-3H2,1H3,(H2,8,11)(H,9,10)(H,12,13)/t5-/m0/s1
InChi Key
KSMRODHGGIIXDV-YFKPBYRVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 g

    $49

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    100 g

    $93

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    250 g

    $182

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    500 g

    $339

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    Product Description

    N-acetyl-L-Glutamine is an acetylated form of the conditionally essential amino acid L-glutamine (Item No. 23716). It decreases infarct volume and prevents neuronal apoptosis in the substantia nigra in a rat model of cerebral ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).1 N-acetyl-L-Glutamine (8.28 g/animal per day) prevents decreases in body weight in protein-energy malnourished pigs.2 Formulations containing N-acetyl-L-glutamine have been used as dietary supplements.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, R., Yang, N., Ji, C., et al. Neuroprotective effects of Aceglutamide on motor function in a rat model of cerebral ischemia and reperfusion. Restor. Neurol. Neurosci. 33(5), 741-759 (2015).

    2. López-Pedrosa, J.M., Manzano, M., Baxter, J.H., et al. N-acetyl-L-glutamine, a liquid-stable source of glutamine, partially prevents changes in body weight and on intestinal immunity induced by protein energy malnutrition in pigs. Dig. Dis. Sci. 52(3), 650-658 (2007).