A tyrosinase inhibitor and cosmeceutical peptide
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Decapeptide-12 (acetate)

Item No. 35400

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptophyl-L-tyrosine, acetate
Synonyms
  • YRSRKYSSWY
Molecular Formula
C65H90N18O17 • XC2H4O2
Formula Weight
1395.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: soluble
λmax
221 nm
SMILES
OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@@H](NC([C@H](CO)NC([C@H](CO)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O.CC(O)=O
InChi Code
InChI=1S/C65H90N18O17.C2H4O2/c66-24-4-3-9-45(76-55(91)47(11-6-26-73-65(70)71)77-60(96)51(32-84)81-57(93)46(10-5-25-72-64(68)69)75-54(90)43(67)27-35-12-18-39(87)19-13-35)56(92)78-48(28-36-14-20-40(88)21-15-36)58(94)82-53(34-86)62(98)83-52(33-85)61(97)79-49(30-38-31-74-44-8-2-1-7-42(38)44)59(95)80-50(63(99)100)29-37-16-22-41(89)23-17-37;1-2(3)4/h1-2,7-8,12-23,31,43,45-53,74,84-89H,3-6,9-11,24-30,32-34,66-67H2,(H,75,90)(H,76,91)(H,77,96)(H,78,92)(H,79,97)(H,80,95)(H,81,93)(H,82,94)(H,83,98)(H,99,100)(H4,68,69,72)(H4,70,71,73);1H3,(H,3,4)/t43-,45-,46-,47-,48-,49-,50-,51-,52-,53-;/m0./s1
InChi Key
LVRRLUMIJIYARW-FIKOAUDQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $44

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    5 mg

    $196

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    10 mg

    $347

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    Product Description

    Decapeptide-12 is a tyrosinase inhibitor and cosmeceutical peptide.1 It inhibits mushroom tyrosinase (IC50 = 40 µM), as well as human tyrosinase by 35% when used at a concentration of 100 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hariri, R.J., Saeedi, M., and Akbarzadeh, T. Naturally occurring and synthetic peptides: Efficient tyrosinase inhibitors. J. Pept. Sci. 27(7), e3329 (2021).