An active metabolite of albendazole
Related Products
Labeled Version(s)
35129Albendazole sulfone-d3
Parent Compound(s)
23705Albendazole
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Albendazole sulfone

Item No. 35445

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[6-(propylsulfonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester
CAS Number
75184-71-3
Synonyms
  • ABZ-SO2
  • ABZ-SOO
Molecular Formula
C12H15N3O4S
Formula Weight
297.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: soluble
λmax
223 nm
SMILES
O=S(C(C=C1N2)=CC=C1N=C2NC(OC)=O)(CCC)=O
InChi Code
InChI=1S/C12H15N3O4S/c1-3-6-20(17,18)8-4-5-9-10(7-8)14-11(13-9)15-12(16)19-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChi Key
CLSJYOLYMZNKJB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $156

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    10 mg

    $264

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    25 mg

    $618

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    Product Description

    Albendazole sulfone is an active metabolite of the benzimidazole anthelmintic albendazole (Item No. 23705).1,2 It inhibits spore formation of E. hellem, E. cuniculi, and E. intestinalis in vitro (IC90s = <0.0001, <0.001, and <0.1 µg/ml, respectively).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baliharová, V., Velík, J., Fimanová, K., et al. Inhibitory effect of albendazole and its metabolites on cytochromes P450 activities in rat and mouflon in vitro. Pharmacol. Rep. 57, 97-106 (2005).

    2. Ridoux, O., and Drancourt, M. In vitro susceptibilities of the microsporidia Encephalitozoon cuniculi, Encephalitozoon hellem, and Encephalitozoon intestinalis to albendazole and its sulfoxide and sulfone metabolites. Antimicrob. Agents and Chemother. 42(12), 3301-3303 (1998).