A synthetic intermediate
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2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide

Item No. 35536

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-chloro-N-methyl-N-(4-nitrophenyl)-acetamide
CAS Number
2653-16-9
Molecular Formula
C9H9ClN2O3
Formula Weight
228.6
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 11 mg/mlPBS (pH 7.2): 0.25 mg/ml
SMILES
O=C(CCl)N(C)C1=CC=C([N+]([O-])=O)C=C1
InChi Code
InChI=1S/C9H9ClN2O3/c1-11(9(13)6-10)7-2-4-8(5-3-7)12(14)15/h2-5H,6H2,1H3
InChi Key
JAWLWNKATJAODJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $49

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    250 mg

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    500 mg

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    1 g

    $339

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    Cayman Chemical
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    Product Description

    2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide is a synthetic intermediate.1 It has been used in the synthesis of maternal embryonic leucine zipper kinase (MELK) inhibitors with anticancer activity.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Edupuganti, R., Taliaferro, J.M., Wang, Q., et al. Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. Bioorg. Med. Chem. 25(9), 2609-2616 (2017).